GLP-1 stands for glucagon-like peptide-1. It’s a hormone your body naturally makes in response to food. One of its main jobs is to help manage blood sugar. It does this by:
Stimulating your pancreas to release insulin (which lowers blood sugar)
Slowing down how fast your stomach empties (so you feel full longer)
Reducing the release of another hormone called glucagon (which raises blood sugar)
Acting on the brain to decrease appetite
In people with type 2 diabetes or metabolic challenges, the body either doesn’t make enough GLP-1 or doesn’t respond to it properly.
GLP-1 receptor agonists (often mistakenly called GLP-1 inhibitors) mimic your body’s natural GLP-1. They bind to the same receptors in your body and amplify its effects, helping regulate your blood sugar and appetite more effectively.
Here’s what that means in practical terms:
Better blood sugar control: These medications help your body release insulin only when it’s needed, which helps avoid low blood sugar episodes (especially compared to older diabetes medications).
Slowed digestion: Your stomach empties more slowly, which means you feel fuller with less food.
Reduced appetite: Many people naturally eat less, without having to fight cravings.
Weight loss: While not the original purpose of these medications, many patients experience significant and sustained weight loss—especially those on higher-dose versions like Wegovy or Zepbound.
GLP-1 medications were originally developed for type 2 diabetes, but are now also approved for people with obesity or weight-related health conditions. They’re not magic pills, and they work best when combined with lifestyle changes like healthy eating and movement.
If you’re considering a GLP-1 medication, we’ll look at your health history, goals, and potential side effects to determine if it’s the right option for you.
Like all medications, GLP-1 drugs have potential side effects. The most common ones are:
Nausea
Vomiting
Diarrhea or constipation
Mild fatigue
Rarely, pancreatitis or gallbladder issues
Most of these symptoms are manageable and tend to improve as your body adjusts.
GLP-1 medications can be life-changing, but they’re tools—not cures. They help create space for healthier habits to take root, and they can be part of a bigger strategy to improve long-term health. Whether you’re managing diabetes, trying to lose weight, or both, it’s important we approach this as a team—with trust, effort, and empathy.
If you have questions about whether GLP-1 therapy might be right for you, don’t hesitate to reach out. Together, we can make a thoughtful, informed plan that fits you.
At Princeton Sports and Family Medicine, P.C., our doctors specialize in sports medicine services, including weight loss, exercise counseling and physician services to assess your risk for injury and assist in your performance goals.
Call or click to book a session with our professionals at Princeton Sports and Family Medicine, P.C. In addition to problem-focused visits, we offer sports performance evaluations to stop problems before they start. Plan your visit today!
